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Home » Liquid » Taste Making Resins for Norfloxacin

Taste Making Resins for Norfloxacin

Polacrillin Potassium is derived from crosslinked Polymer of Polycarboxylic Acids & has a K+ ionic form. Polacrillin Potassium is a very high purity Polymer finding use in pharmaceutical formulations as a Tablet Disintegrant in the oral dosage formulations.
Taste Masking Agent - 104
Taste Masking Agent - 104 is derived from crosslinked polymer of Methacrylic acid. Taste Masking Agent - 104 has carboxylic acid functionally which is enables its use as a TASTE MASKING AGENT, while the cross linked porous nature makes its suitable as a SUSTAIN RELEASE AGENT.
Specifications
The Physical & Chemical properties are as under :
Physical Properties
Appearance White to off white free flowing powder.
Solubility Insoluble in water & common solvents
Moisture Content 10% max.
Particle Size 1% max. retained on 100 BSS &
70% min. passing through 200 BSS

Chemical Properties
Polymeric Functional Group Carboxylic Acid
Sodium Content 0.2% max.
Iron Content as Fe 100 ppm max.
Heavy Metals as Pb 10 ppm max.
Arsenic Content as As 3 ppm max.

Applications
Taste Masking Agent : A drug polymer adduct can be synthesized due to the ionic bonding between the bitter drug and the polymer thus masking the objectionable bitter taste of the drug. Since the polymer drug adduct so formed is tasteless in the mouth, but it dissociates in the acidic pH of the stomach, the bio availability of the drug is not effected.

Examples : Norfloxacin, Ofloxacin

Sustain Release of Nicotine : The crosslinked porous polymer facilitates sustain release of nicotine.
Toxicity
Taste Masking Agent - 104 is high molecular weight polymer so can't be absorbed by body tissued & is safe for human consumption. It has no any physiological action at recommended dosage & it is non-toxic.
Storage
Store in tightly container. Keep away from moisture. If moisture is absorbed, dry at 900C to 1000C to remove moisture content below 10%.
Packing
5 kg, 20 kg, in Corrugated Box.

Note : Application notes and MSDS sheet can be made available on request



Taste Masking Rosin - 134
Taste Masking Rosin - 134 is derived from crosslinked polymer of acrylic acid and has a K + ionic form. Taste Masking Rosin - 134 is a very high purity polymer finding use in pharmaceutical formulations for TASTE MASING of certain drugs, particularly B-lactum antibiotics.
Specifications
The Physical & Chemical properties are as under :
Physical Properties
Appearance White to off white free flowing powder.
Solubility Insoluble in water & common solvents
Moisture Content 10% max.
Particle Size 1% max. retained on 100 BSS &
70% min. passing through 200 BSS

Chemical Properties
Polymeric Functional Group Carboxylic Acid
Potassium content Potassium content 20.6 to 25.1%
Sodium Content 0.2% max.
Iron Content as Fe 100 ppm max.
Heavy Metals as Pb 10 ppm max.
Arsenic Content as As 3 ppm max.

Applications
Taste Masking Agent : Taste Masking Rosin - 134 forms complex with drug & mask it's bitter taste. This complex formed does not dissociate in saliva pH but, dissociate in acidic pH of stomach. Thus this complex is tasteless without affecting its bio availability. This technique helps to formulate palatable & chewable tablets, dispersible tablet & suspensions of bitter taste drugs.

Examples : Chloroquine Phosphate, Ciprofloxacin HCL, Chloroquine Sulphate, Dextromethorphan Hydrobromide, Metoclopramide Hydrochloride.
Toxicity
Taste Masking Rosin - 134 is high molecular weight polymer so can't be absorbed by body tissues & is safe for human consumption. It has no any physiological action at recommended dosage & it is non-toxic.
Storage
Store in tightly closed container. Keep away from moisture. If moisture is absorbed dry at 900C to 1000C to remove moisture content below 10%.
Packing
5 kg, 20 kg, in Corrugated Box.